As always in League of Legends, Patch 11.10 will have some champions who get the short end of the stick. Some of these champions probably won't see any action at all this entire patch but it's important to know who to stay away from, if not for yourself then for the benefit of your team.
5 Worst Mid Laners in League of Legends Patch 11.10
Sadly this once great champion is now a complete afterthought in the mid lane. Azir's problem is not only that he isn't meta but his kit as a champion is extremely difficult to use. So even if you wanted to utilize this champion you'd be severely handicapping yourself.
Don't let the miraculous plays of these pro level mid laners fool you, Orianna is not for the faint of heart. She has very useful tools and mobility which makes her a solid pick at the pro level for those that are mechanically sound and seasoned with her. But for those looking to climb their way to higher ranks it's not worth the hassle for you to even think about using this champion.
What was said for Orianna can be applied here as well. Syndra's damage potential is absolutely scary. But it requires a lot of set up and maneuvering that most players aren't willing to commit to. If you understand how to play Syndra she can be a devastating pick but otherwise she can be very frustrating as a champion pick.
Twisted Fate is a situational play, you'll need to understand how his cards work and how to implement them in situations to achieve the any kind of success with him. Although mages are extremely powerful right now if you can't play around your cards and efficiently use your ultimate to manipulate fights your team will essentially be playing 4-vs-5.
With one of the lowest win and pick rates Zoe finishes this list off because her kit just isn't viable in any way. Her ultimate is useless, her normal skills outside of her Q don't do much to help players that need to handle their matchup. It's always a battle to sustain until team fighting begins and that makes her a terrible pick as a champion.