The Mewtwo moveset in Pokémon GO allows trainers to go in a lot of different directions, however, it remains clear among the strongest trainers which of its moves are best to use.
Mewtwo remains, both in lore and in games, one of the strongest Pokémon. With its CP ceiling of over 4000, here are the best moves trainers should be using with Mewtwo to dominate the competition.
Mewtwo Moveset Pokémon GO: Best Moves Available
For starters, it is important to point out that there are two versions of it in Pokémon GO—Mewtwo and Armored Mewtwo.
While the Armored Mewtwo learns many attacks that are physical attacks, the regular Mewtwo learns many moves that are special attacks. Additionally, since the regular Mewtwo is dishes out more damage than the albeit sturdier Armored option, Mewtwo a better choice for Raid Battles and Armored Mewtwo a stronger option for Trainer Battles.
The best main move trainers should run on Mewtwo is Psystrike thanks to its astonishing 47 DPS.
Although Mewtwos only know Psystrike when they're caught during special events, it is absolutely worth powering up a Mewtwo that knows Psystrike even if trainers already have one that doesn't. Psystrike deals far more damage than Psychic or Future Sight, and is arguably the best possible Psychic-type charged move.
As for which quick move trainers should opt for between Confusion and Psycho Cut, it is a bit more debatable.
While Psycho Cut is viable in certain cases, Confusion is superior in most PvE situations as it takes down opposing Pokémon in fewer seconds thanks to its additional 5 DPS.
Overall, the best moveset for Mewtwo is the quick move Confusion and the charged move Psystrike (or Psychic if Psystrike isn't available).